Publications

Scherer SD, Riggio AI, Haroun F, Derose YS, Ekiz HA, Fujita M, Toner J, Zhao L, Li Z, Oesterreich S, Samatar AA, Welm AL (2021). An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer. Breast Cancer Res, 23(1):100.

Stephens WZ, Kubinak JL, Ghazaryan A, Bauer KM, Bell R, Buhrke K, Chiaro TR, Weis AM, Tang WW, Monts JK, Soto R, Ekiz HA, O'Connell RM, Round JL (2021). Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition. Cell Rep, 37(5):109916.

Lai SA, Gundlapalli H, Ekiz HA, Jiang A, Fernandez E, Welm AL (2021). Blocking Short-Form Ron Eliminates Breast Cancer Metastases through Accumulation of Stem-Like CD4 + T Cells That Subvert Immunosuppression. Cancer Discov, 11:3178-97.

Huffaker TB, Ekiz HA, Barba C, Lee S, Runtsch MC, Nelson MC, Bauer KM, Tang WW, Mosbruger TL, Cox JE, Round JL, Voth WP, O'Connell RM (2021). A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages. Nat Commun, 12(1):2620.

Cortes-Selva D, Gibbs L, Ready A, Ekiz HA, O'Connell RM, Rajwa B, Fairfax CF (2021). Maternal schistosomiasis impairs offspring Interleukin-4 production and B cell expansion. PLoS pathogens, 17(2):e1009260.

Syage AR, Ekiz HA, Skinner DD, Stone C, O'Connell RM, Lane TE (2020). Single-Cell RNA Sequencing Reveals the Diversity of the Immunological Landscape following Central Nervous System Infection by a Murine Coronavirus. J Virol, 94(24):e01295-20.

Mangale V, Syage AR, Ekiz HA, Skinner DD, Cheng Y, Stone CL, Brown RM, O'Connell RM, Green KN, Lane TE (2020). Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system. Glia, 68(11):2345-2360.

Ekiz HA, Conley CJ, Stephens WZ, O'Connell RM (2020). CIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments. BMC Bionformatics, 21(1):191.

Ekiz HA, Ramstead AG, Lee S, Nelson MC, Bauer KM, Wallace JA, Hu R, Round JL, Rutter J, Drummond MJ, Rao DS, O'Connell RM (2020). T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation. J Immunol, 204(8):2064-2075.

Snook JP, Soedel AJ, Ekiz HA, O'Connell RM, Williams MA (2020). Inhibition of SHP-1 Expands the Repertoire of Antitumor T Cells Available to Respond to Immune Checkpoint Blockade. Cancer Immunol Res, 8(4):506-517.

Ramstead AG, Wallace JA, Lee H, Bauer KM, Tang WW, Ekiz HA, Lane TE, Cluntun AA, Bettini ML, Round JL, Rutter J, O'Connell RM (2020). Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development. Cell Reports, 30(9):2889-2899.e6.

Petersen C, Bell R, Klag KA, Lee S, Soto R, Ghazaryan A, Buhrke K, Ekiz HA, Ost KS, Boudina S, O'Connell RM, Cox JE, Villanueva CJ, Stephens WZ, Round JL (2019). T cell-mediated regulation of the microbiota protects against obesity. Science, 365(6451):eaat9351.

Ekiz HA, Huffaker TB, Grossman AH, Stephens WZ, Williams MA, Round JL, O'Connell RM (2019). MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers. JCI Insight, 4(6):e126543.

Fix DK, Ekiz HA, Petrocelli JJ, Mckenzie AM, Mahmassani ZS, O'Connell RM, Drummond MJ (2019). Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy. Aging Cell, 20(9):e13448.

Ekiz HA, Lai SA, Gundlapalli H, Haroun F, Williams MA, Welm AL (2018). Inhibition of RON kinase potentiates anti-CTLA-4 immunotherapy to shrink breast tumors and prevent metastatic outgrowth. Oncoimmunology, 7(9):e1480286.

Drobysheva D, Smith AS, Mcdowell M, Guillen KP, Ekiz HA, Welm BE (2015). Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential. Breast Cancer Res, 17(1):132.

Mckenzie JA, Liu T, Jung JY, Jones BB, Ekiz HA, Welm AL, Grossman D (2013). Survivin promotion of melanoma metastasis requires upregulation of α5 integrin. Carcinogenesis, 34(9):2137-44.

Eyob H, Ekiz HA, Welm AL (2013). RON promotes the metastatic spread of breast carcinomas by subverting antitumor immune responses. Oncoimmunology, 2(9):e25670.

Eyob H, Ekiz HA, Derose YS, Waltz SE, Williams MA, Welm AL (2013). Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity. Cancer Discov, 3(7):751-60.

Ekiz HA, Can G, Baran Y (2012). Role of autophagy in the progression and suppression of leukemias. Crit Rev Oncol Hematol, 81(3):275-85.

Avci CB, Yilmaz S, Dogan ZO, Saydam G, Dodurga Y, Ekiz HA, Kartal M, Sahin F, Baran Y, Gunduz C (2011). Quercetin-induced apoptosis involves increased hTERT enzyme activity of leukemic cells. Hematology, 16(5):303-7.

Ekiz HA, Baran Y (2011). Bioactive sphingolipids in response to chemotherapy: a scope on leukemias. Anticancer Agents Med Chem, 11(4):385-97.

Can G, Ekiz HA, Baran Y (2011). Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells. Hematology, 16(2):95-9.

Ekiz HA, Baran Y (2010). Therapeutic applications of bioactive sphingolipids in hematological malignancies. International Journal of Cancer, 127(7):1497-506.

Kosova B, Tezcanli B, Ekiz HA, Cakir Z, Selvi N, Dalmizrak A, Kartal M, Gunduz U, Baran Y (2010). Suppression of STAT5A increases chemotherapeutic sensitivity in imatinib-resistant and imatinib-sensitive K562 cells. Leuk Lymphoma, 51(10):1895-901.

Ekiz HA, Can G, Gunduz U, Baran Y (2010). Nilotinib significantly induces apoptosis in imatinib-resistant K562 cells with wild-type BCR-ABL, as effectively as in parental sensitive counterparts. Hematology, (1):33-8.