O'Connell RM

Latest

• Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition
• A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages
• Maternal schistosomiasis impairs offspring Interleukin-4 production and B cell expansion
• Single-Cell RNA Sequencing Reveals the Diversity of the Immunological Landscape following Central Nervous System Infection by a Murine Coronavirus
• Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system
• CIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments
• T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation
• Inhibition of SHP-1 Expands the Repertoire of Antitumor T Cells Available to Respond to Immune Checkpoint Blockade
• Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development
• T cell-mediated regulation of the microbiota protects against obesity
• Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy
• MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers